However, a recent meta-analysis found no link between the two. Further studies looking at this relationship would be beneficial [ 57 , 23 , 58 , 59 ]. Metabolic syndrome is 2 or more of the following conditions including insulin resistance , high blood pressure, blood fat abnormalities dyslipidemia , and obesity. Independent of other risk factors, a number of clinical studies have found that elevated levels of GGT increased the risk of metabolic syndrome [ 29 , 30 , 31 ].
GGT may be useful at predicting cancer risk and disease outcome. According to several clinical studies, elevated GGT levels increase overall cancer risk [ 32 , 60 ]. In a few early studies, elevated GGT levels have been associated with some types of cancer [ 61 , 62 ]:.
One study in 10k Korean men found that the risk of chronic kidney disease was greater in patients with elevated GGT levels. Another study of 9. Elevated levels of GGT may be associated with an increased risk of chronic kidney disease in specific populations. One clinical study in 2.
In a study of people, GGT was elevated in patients with hyperthyroidism. In a larger study of 1. GGT was slightly increased in patients with hypothyroidism in one study and decreased in another study.
Additional research is needed to clarify the relationship between GGT and thyroid disease [ 76 , 77 ]. Bone mineral density BMD represents overall bone health and strength. One clinical study in people found people with high GGT levels have low BMD independent of alcohol consumption [ 78 ].
High levels of GGT usually indicate present disease or a higher risk of disease. Here we give a summary of the factors that increase levels of GGT. Several medications increase GGT levels and must be taken into consideration when interpreting test results. These include older anti-seizure medications such as phenytoin, phenobarbital, and carbamazepine [ 79 , 80 , 81 , 82 ]. GGT levels are elevated following prolonged alcohol use. As drinking increases, the level of GGT in the blood also rises [ 17 , 18 , 19 ].
Red meat intake over 10 years increased GGT levels [ 10 ]. Several clinical studies have found that elevated levels of thyroid hormone increased levels of GGT in patients with hyperthyroidism [ 84 , 74 ]. GGT is ultimately just a biomarker that indicates an underlying problem. Talk to your doctor to identify any underlying health conditions and determine the best strategies for treating those.
Alcohol abuse increases GGT levels. GGT is only slightly elevated in moderate drinkers, but the increase is relevant. The best way to lower GGT is to simply abstain from alcohol use. Many fruits and vegetables contain moderate to high amounts of natural antioxidants. Support liver health by eating fruits and veggies while limiting added sugars and high-calorie or high-sodium dressings.
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Read More ». Trending Diseases. Add fish oil supplements to your diet. Choose a high-dose fish oil supplement, and take 4 grams 0. Fish oil may lower GGT levels related to non-alcoholic fatty liver disease. National Institutes of Health Go to source Talk to your doctor before adding this supplement to your diet, and follow the directions on the bottle. Try glutathione supplements alongside other changes.
Glutathione may reduce levels of GGT in some people. In many cases, higher levels of glutathione in your body will result in lower GGT levels. However, it doesn't work for everyone. National Institutes of Health Go to source Talk to your doctor before adding glutathione to your regimen, and always follow the directions on the label.
Stay away from environmental toxins, such as lead. Environmental toxins stress your body and can affect your liver function. They can cause you to gain weight by affecting your endocrine system, which can increase your risk of high GGT. Additionally, toxins can build up in your system and elevate your GGT levels.
Minimizing your exposure can keep your GGT levels in check. National Institutes of Health Go to source Here are environmental toxins you should avoid, especially if you already have high GGT levels: Lead Cadmium Dioxide Pesticides, especially those containing organochlorine.
Method 3. Avoid drinking more than 1 or 2 alcoholic drinks per day. High levels of GGT in the blood can also stem from frequent alcohol consumption, even if the liver is in fine condition. When a person drinks alcohol excessively, it activates a metabolic pathway which releases GGT to help breakdown the alcohol. So, to lower your GGT, work on drinking less alcohol. The guidelines for moderate drinking suggest that women under 65 have up to 1 drink a day, and that men under 65 have up to 2 drinks a day.
Increase your daily coffee consumption. Coffee, in general, protects the liver from substances that would otherwise harm it, including GGT. Have 2 or 3 cups in the morning, and another cup or 2 later in the day. In individuals with high levels of GGT—whether from a liver condition or from alcohol use—frequent coffee drinking can lower the amount of GGT in your blood.
Excessive coffee consumption can carry health risks. Adults should avoid drinking more than about 4 mugs of coffee each day. Ask your doctor for a GGT test if you drink excessively. Excessive drinking is defined as consuming, on average, alcoholic drinks per day. Visit your doctor, and ask them to administer bloodwork to measure your GGT levels. Your doctor will draw blood from a vein in your arm, and send it to a lab for testing.
Talk to your doctor about all of the medicines and supplements you're taking, including those available over-the-counter. Expect your lab results to take at least a few hours but possibly a few days to be ready.
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